Amniotic membraneAmniotic membrane (AM) transplantationTransplantation (AMT) is a surgically complex techniqueTechnique in ocular surfaceOcular surface therapyTherapy. The beneficial mechanical and biological qualities of AM provide multiple options for the surgical and pharmacological treatmentTreatment of corneal and conjunctival diseases. The wide range of indicationsIndication requires individual surgical plans for the AMT. The AM can serve as a substrate for substituting corneal and conjunctival tissues and can be integrated into the ocular tissues in multiple forms in correlation with the indicating pathology and surgical techniqueTechnique. The various clinical applications for AMT usage in an ophthalmic setting, ranging from commonly used applications to less mainstream approaches can often be identified in postoperative histological examinations (integrationIntegration patterns).