Corneal degenerations are non-hereditary corneal disorders secondary to local or systemic diseasesSystemic diseases or related to age. They are often associated with chronic light exposure and may occur after inflammationInflammation. A late onset with deposition of material, tissue thinning, and vascularization characterizes them. The main age-related forms are bilateral and are represented by arcus lipoides, limbal girdle, Hassall–Henle warts at the peripheral Descemet membrane, and crocodile shagreen. Degenerations with tissue thinning comprise Fuchs–Terrien marginal degeneration, furrow degeneration and corneal dellen. The group characterized by material deposition is composed predominantly by Salzmann nodular degeneration (“Plus disease”), band keratopathy, lipid keratopathy, spheroidal keratopathy and pigment deposition forms. Some of them might induce severe visual impairment while the others are rather innocuous. The correct diagnosisDiagnosis and follow-up are mandatory for the appropriate typically minimal invasive therapyTherapy to maintain or restore visual function and prevent corneal pain.