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Fuchs endothelial corneal dystrophyCorneal dystrophy (FECD) manifests typically in the fifth or sixth decade of life. Focal posterior collagenous excrescences in the central corneaCornea, so-called guttaeGuttae, are the diagnostic hallmark on slit-lamp exam. In FECD, progressive endothelial dysfunction leads to corneal edemaCorneal edema. Chronic edema results in characteristic morphological and anatomical changes in all corneal layers that impair corneal transparency and optics. Endothelial keratoplastyKeratoplasty promises near complete visual rehabilitationVisual rehabilitation by replacing the abnormal Descemet membrane and corneal endotheliumCorneal endothelium if remodeling in the host corneaCornea is not too advanced.

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Fuchs Endothelial Corneal Dystrophy FECD

  • 章节

  • 发表日期：

    2025年

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  • Katrin Wacker,
  • Thomas Reinhard

摘要

Fuchs endothelial corneal dystrophyCorneal dystrophy (FECD) manifests typically in the fifth or sixth decade of life. Focal posterior collagenous excrescences in the central corneaCornea, so-called guttaeGuttae, are the diagnostic hallmark on slit-lamp exam. In FECD, progressive endothelial dysfunction leads to corneal edemaCorneal edema. Chronic edema results in characteristic morphological and anatomical changes in all corneal layers that impair corneal transparency and optics. Endothelial keratoplastyKeratoplasty promises near complete visual rehabilitationVisual rehabilitation by replacing the abnormal Descemet membrane and corneal endotheliumCorneal endothelium if remodeling in the host corneaCornea is not too advanced.