Erectile dysfunction (ED) is one of the most prevalent sexual disorders in our society. Its main risk factors are age, diabetes mellitus, hypertension, dyslipidaemia, metabolic syndrome, obesity, sedentary lifestyle, coronary artery disease, lower urinary tract symptoms and pelvic surgeries. ED is an early symptom of cardiovascular disease and is a strong predictor of coronary artery disease. Its diagnosis is based on a detailed medical and sexual history. From a clinical standpoint, ED is subdivided in primary organic or primary psychogenic. ED management requires modifying reversible risk factors, including lifestyle or drug-related changes. It exists a large range of treatments for ED and they should be chosen based on patient’s preferences and expectations. Among the currently available ED treatments, we can find oral therapy with phosphodiesterase 5 inhibitors, low-intensity shockwave therapy, vacuum devices, topical/intraurethral/intracavernosal medications and penile prosthesis.