While benefits of mindfulness meditation (MM) have been well known in psychological and physiological fields, researchers find weaknesses in many studies seeking to establish such benefits for managers. This work presents empirical results drawn from a randomized pretest-posttest experimental group study linking meditation to leadership skills. Using a self-perception of leadership skills (SPLS) instrument constructed from the Leader Practice Inventory (LPI) and the Moral Competence Inventory (MCI) and validated with a pilot study (N = 20), we conducted the study for a period of 12 weeks to learn the effect of MM in its secularized Vipassana form on senior managers (N = 64) randomly selected from companies registered in London. The effect was measured on five individual skills of leadership: leader as a role model, inspiring a shared vision, demonstrating moral intelligence, enabling others to act, and encouraging the heart/motivating, individually and collectively. We show that meditation statistically significantly enhances self-perception of leadership competencies as a bundle of all five skills and the individual skills of inspiring a shared vision, demonstrating moral intelligence and encouraging the heart/motivating, which the literature identifies as the relationship building skills. Interpretations with directions for further research are provided.