Physiotherapy is a protracted process that necessitates periodic follow-ups, and its application is extensive, encompassing a broad range of patients from newborns to the elderly. The scope of physiotherapy is diverse, encompassing domains such as the neurological, musculoskeletal, cardiovascular, and post-operative sectors. The adoption of home-based rehabilitation has been shown to enhance patient comfort during treatment and reduce healthcare expenditures. This approach also streamlines patient monitoring and management by facilitating regular follow-ups by physiotherapists. Historically, the concept of physiotherapy delivered in the home environment has been often compared with its clinic-based counterpart. However, in the contemporary context, it is becoming increasingly impractical for patients to undergo prolonged treatment in clinics. The development of home-based rehabilitation represents a significant opportunity for investment in healthcare. In this regard, the utilization of artificial intelligence, the advancement of telerehabilitation methodologies, the facilitation of concurrent access for multiple patients with remote monitoring, and the optimization of manpower utilization through the integration of wearable technology are pivotal advancements. This entry will present developments and recommendations regarding home-based rehabilitation, with a detailed discussion to follow for patients, caregivers, and clinicians.