The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been one of the most disruptive global events of the twenty-first century, leading to widespread public health challenges and exacerbating preexisting vulnerabilities among various populations. This chapter explores the profound impact of COVID-19 on disability, both as a direct consequence of severe acute infection and through the long-term sequelae known as long COVID. The persistence of symptoms, including respiratory, neurological, musculoskeletal, and psychological complications, has contributed to significant disabilities that affect quality of life, work performance, and social participation. The pandemic disproportionately affected people with disabilities (PwDs), who faced increased risks of severe disease, disruptions in healthcare access, and exacerbation of existing socioeconomic challenges. The financial and functional implications of these disabilities are discussed, highlighting the urgent need for inclusive policies and adaptive healthcare systems to address the ongoing and long-term effects of the pandemic on this vulnerable population as well as prepare for potential new crises.