The World Health Organization estimates that 1.3 billion people worldwide experience significant disability. One of the important contributors to disease-adjusted life years are chronic infections. The most common age group that gets affected by disability due to infections is younger children. Other important risk groups include the elderly and immunocompromised patients. Several infectious agents can in the long run cause disability of some or other kind. These agents affect the body tissues in a varied manner to produce the impairment of function and disability.