This chapter explores the essential role of multidisciplinary approaches in the management of pain among individuals with disabilities. It highlights the prevalence and types of chronic pain experienced by disabled populations and the complex interplay between disability and pain. This chapter emphasizes the importance of a holistic, team-based approach to pain management, incorporating medical, psychological, and rehabilitative strategies. Key areas of focus include personalized pain management plans, pharmacological and non-pharmacological treatments, and the integration of complementary and alternative medicine. This chapter also discusses the roles of various healthcare professionals, including physicians, physical therapists, psychologists, and occupational therapists, in delivering comprehensive pain management. Practical guidelines for implementing multidisciplinary pain management programs and policy recommendations to improve access to these services are provided. This chapter serves as a valuable resource for healthcare providers and policymakers seeking to enhance pain management practices for individuals with disabilities.