This chapter delves into the crucial intersection of cardiovascular health and disability, highlighting prevention and management strategies tailored for individuals with disabilities. It begins by examining the prevalence of cardiovascular diseases (CVD) in disabled populations and identifying specific risk factors that exacerbate their health outcomes. The chapter discusses diagnostic challenges and adaptations required for effective cardiovascular screening in these individuals. Treatment considerations are explored, emphasizing personalized care approaches, medication management, and lifestyle modifications. Rehabilitation strategies and the importance of a multidisciplinary approach to improving cardiovascular health are underscored. The chapter also covers psychosocial support, the role of nutrition and vitamins, and the development of comprehensive care plans to enhance the overall health and quality of life for disabled individuals with cardiovascular conditions. Practical guidelines for healthcare providers and policy recommendations to improve healthcare access and outcomes are provided, making this chapter an essential resource for managing cardiovascular health in disabled populations.