Blue rubber bleb nevus syndrome (BRBNS) is characterized by multiple nevi affecting the skin and gastrointestinal tract. Gastrointestinal tract blebs can appear from the mouth to the anus and are a cause of bleeding, iron deficiency anemia, diarrhea, volvulus, intestinal infarction, intussusception, rectal prolapse, and airway compromise. Concurrent arteriovenous malformations (AVMs) may be seen.