This chapter addresses the persistent division between physical and mental healthcare, termed the “medical schism,” and its significant impact on the field of Oral and Maxillofacial Surgery (OMFS)Oral and maxillofacial surgery (OMFS). Rooted in Cartesian dualism, the schism has led to fragmented patient care, where physical ailments are treated independently from psychological ones, often to the detriment of patient outcomes. By exploring various OMFS case studies—ranging from orthognathic surgery and body dysmorphic disorder to facial trauma and post-surgical depression—the chapter highlights the importance of integrating mental health assessments and psychological support into surgical care. Drawing on interdisciplinary research, this work advocates for routine mental health screenings, comprehensive referral pathways, and interdisciplinary collaboration to bridge the gap between physical and psychological health. Ultimately, the chapter calls for a paradigm shift toward holistic patient care, emphasizing that addressing both physical and mental dimensions is essential for enhancing recovery, reducing complications, and improving patient quality of life in OMFS practice.