In the last few decades, there has been an explosion in the field of ophthalmic genetics from advances in genome sequencing to gene therapy and gene editing. These are complex techniques that offer unparalleled treatment avenues for several forms of retinal diseases. This chapter aims to provide an in-depth narrative review of the literature in the topic of gene editing with CRISPR-Cas9.

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Gene Editing/CRISPR

  • Thales A. C. de Guimaraes,
  • Stephen H. Tsang,
  • Thiago Cabral

摘要

In the last few decades, there has been an explosion in the field of ophthalmic genetics from advances in genome sequencing to gene therapy and gene editing. These are complex techniques that offer unparalleled treatment avenues for several forms of retinal diseases. This chapter aims to provide an in-depth narrative review of the literature in the topic of gene editing with CRISPR-Cas9.