Scientific challenges for climate change resilience include climate resilience communication action formulation and implementation scientific basis improving. This mainly involves improving climate change resilience communication efficiency theoretical tools, methodologies, knowledge bodies, and decision-making tools. This article proposes the AgriClimCom scientific framework for agricultural resilience to climate change communication in sub-Saharan Africa. It suggests an approach, methodological tools, and specific schemes for the development and implementation of efficient agricultural sector climate change resilience communication actions. The information bodies relate to agriculture climate change impacts, vulnerability factors, resilience solutions, and communication actions target groups and channels. The AgriclimCom scientific framework is a new tool to improve, in indicated contexts, the relevance, efficiency, and impact of agricultural sector climate change resilience communication actions. Such communication actions use the most appropriate communication channels to inform relevant target groups about agriculture climate change impacts, vulnerability factors, and resilience solutions concerned by climate change resilience policies.