Financial crime is a growing threat to the global financial system. In recent years, the financial industry has been undergoing a transformation from a traditional regulatory environment to a new regulatory environment that focuses on thwarting financial crime. The intersection of anti-money laundering and sanctions compliance represents a vital collaboration between the financial sector's initiatives to combat illegal activities and international efforts aimed at restricting the movement of funds to and from individuals, groups, and nations that are under sanctions. This chapter aims to explore the convergence of these two domains, highlight the primary legal challenges that arise, and discuss effective strategies for harmonizing these efforts to enhance their overall effectiveness.