Scholarlink

The origins of humanity are fundamentally intertwined with the microbial world, which shapes multiple aspects of human existence. The signature of the gut microbiota is evident across various elements of human biology and physiological processes. A mutually beneficial and balanced interaction between the host and its gut microbiota is crucial for maintaining both intestinal and systemic health. Alterations in the composition and function of the gut microbiota, often driven by an unhealthy lifestyle, can significantly influence physiological processes leading to an increased prevalence of chronic metabolic disorders, including obesity, liver disease, type 2 diabetes mellitus, cardiometabolic diseases, and premature mortality. Employing gut microbiota and its microbial metabolites as biomarkers for diagnosis and therapeutic targets offers promising strategies for personalized treatments to improve human health.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Metabolic and Endocrinological Aspects of Gut Microbiota

  • 动态工具书词条

  • 发表日期：

    2026年

查看全文
  • Susanna Longo,
  • Lorenzo Antonetti,
  • Viviana Casagrande,
  • Alessandra Antonucci,
  • Rocco Mollace,
  • Rossella Menghini,
  • Massimo Federici

摘要

The origins of humanity are fundamentally intertwined with the microbial world, which shapes multiple aspects of human existence. The signature of the gut microbiota is evident across various elements of human biology and physiological processes. A mutually beneficial and balanced interaction between the host and its gut microbiota is crucial for maintaining both intestinal and systemic health. Alterations in the composition and function of the gut microbiota, often driven by an unhealthy lifestyle, can significantly influence physiological processes leading to an increased prevalence of chronic metabolic disorders, including obesity, liver disease, type 2 diabetes mellitus, cardiometabolic diseases, and premature mortality. Employing gut microbiota and its microbial metabolites as biomarkers for diagnosis and therapeutic targets offers promising strategies for personalized treatments to improve human health.