Bowel and mesenteric injuries due to blunt trauma are relatively uncommon; however, a prompt detection of such lesions is vital in order to decrease mortality and morbidity due to a delayed diagnosis. In addition, since treatment algorithms are conservatively oriented, this increases the need to identify bowel and mesenteric trauma early in the treatment process. Multidetector CT (MDCT) is considered the imaging modality of choice for the diagnosis of bowel and mesenteric traumatic injuries, although the detection of these injuries can be challenging because of the presence of multiple simultaneous injuries and subtle imaging findings. Several CT signs of bowel and mesenteric injuries due to blunt trauma have been described in the literature. The major objective in evaluating these signs is to differentiate significant bowel and mesenteric injuries that require surgical treatment from those that can be conservatively treated. Familiarity with direct and indirect CT findings of blunt bowel and mesenteric injuries as well as the recognition of those CT features requiring surgery is crucial to making a timely and accurate diagnosis.