In the relentless developing of material science, the emerging and promising compound family of two-dimensional transition metal carbide/nitride recently have presented its advent toward three-dimensional printing processes. The principal purpose of this chapter is to illustrate the main features involving the introduction to the state of art of MXene-based nanomaterials into the three-dimensional printing processes, intending to encircle the experimental design, processing, characterization, and applications. The multifunctionality of MXene-based nanomaterials have been accentuated the evaluation of the capabilities and achievements implying three-dimensional printing. With the assistance of the literature history regarding the topic, the veracity of the methods is verified by reviewing the synthesis methodology of the MXene and its relation to three-dimensional printing. Deepening since the discovery of MXene compound family in 2011, as a common axis with three-dimensional printed devices, structural, compositional, and functional properties are analyzed for complete comprehension. This chapter enriches the ongoing dialogue surrounding the progress of three-dimensional printed MXene-based nanomaterial devices within the field of material science, by identifying existing challenges and exploring future opportunities.