This entry discusses some of the best-known and most significant manuscripts associated with early modern women’s authorship written in English. It establishes the importance of manuscript to understanding women’s writing, and focusing on literary examples it considers three main categories of manuscript: presentation manuscripts and fair copies, working manuscripts and drafts, and compilations and miscellanies. While noting some key genres of manuscript written or compiled by women, it offers an overview of some of the “greatest hits” of extant handwritten documents, many of which are available in digital surrogates and in excellent scholarly editions. Major literary manuscript authors include Hester Pulter, Mary Sidney, Mary Wroth, Katherine Philips, and Lucy Hutchinson. Briefer mention is made of several less canonical manuscript writers and compilers, as well as additional types of genres often found in manuscripts, including religious writing, life writing, and domestic recordkeeping. The entry demonstrates the importance of consulting both manuscript and print sources when studying early modern writing.