Hyperlipidemia, a type of dyslipidemia, involves elevated levels of LDL, VLDL, total cholesterol, and triglycerides. It is a major risk factor for atherosclerosis and cardiovascular disease. Therefore, animal models of hyperlipidemia are commonly used to test the lipid-lowering effect of different natural compounds. Among various methods described in the literature, high-fat diet feeding is preferred. Such diets typically include ingredients like cholesterol, lard, sucrose, or fructose.