Scholarlink

Many structural characterization techniques either require a solid sample or for the sample to be placed on a substrate. This can be a challenge when the structure depends on the concentration of environmental parameters such as pH and salt. Small-angle X-ray/neutron scattering (SAXS/SANS) is an excellent tool that can be used for in situ, non-invasive, structural characterization of soft matter and biological systems in solution. In this chapter, we present how to prepare lipid vesicles as a relevant model system for cell membranes and their interactions with surface-active agents. We include a brief introduction of scattering theory and the basics of SAXS/SANS, how to analyze and interpret the data, as well as discussing some complementary techniques that can elucidate different aspects/properties of your sample.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Investigating Peptide–Lipid Membrane Interactions Using Small Angle X-Ray and Neutron Scattering

  • 实验方案

  • 发表日期：

    2026年

查看全文
  • Vladimir Rosenov Koynarev,
  • Kari Kristine Almåsvold,
  • Reidar Lund

摘要

Many structural characterization techniques either require a solid sample or for the sample to be placed on a substrate. This can be a challenge when the structure depends on the concentration of environmental parameters such as pH and salt. Small-angle X-ray/neutron scattering (SAXS/SANS) is an excellent tool that can be used for in situ, non-invasive, structural characterization of soft matter and biological systems in solution. In this chapter, we present how to prepare lipid vesicles as a relevant model system for cell membranes and their interactions with surface-active agents. We include a brief introduction of scattering theory and the basics of SAXS/SANS, how to analyze and interpret the data, as well as discussing some complementary techniques that can elucidate different aspects/properties of your sample.