Scholarlink

Patient-derived tumor xenograft (PDX) models are crucial for understanding brain tumor progression and for pre-clinical evaluation of therapeutic interventions. Luciferase-based bioluminescence imaging offers a non-invasive approach to visualizing and quantifying tumor development across multiple time points. This chapter presents a methodology for employing the IVIS® (in vivo imaging) system to analyze tumor dynamics in luciferase expressing PDX brain tumor models.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Bioluminescent Imaging of Patient-Derived Brain Tumors in Live Mice

  • 实验方案

  • 发表日期：

    2025年

查看全文
  • Dillon McKenna,
  • Chitra Venugopal,
  • Sheila K. Singh

摘要

Patient-derived tumor xenograft (PDX) models are crucial for understanding brain tumor progression and for pre-clinical evaluation of therapeutic interventions. Luciferase-based bioluminescence imaging offers a non-invasive approach to visualizing and quantifying tumor development across multiple time points. This chapter presents a methodology for employing the IVIS® (in vivo imaging) system to analyze tumor dynamics in luciferase expressing PDX brain tumor models.