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Various high-throughput genetic functional screening and physical protein interaction screening methods have been employed to gain a global understanding of how viruses interact with host cells for replication. In this chapter, we provide an overview of the bioinformatics analysis and computational methods of virus–host interactions and highlight their advantages and disadvantages to provide a technical reference for interactive research on virus–host interactomes and the identification of antiviral factors.

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Computational Analysis of Virus–Host Interactomes

  • 实验方案

  • 发表日期：

    2025年

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  • Xin Li,
  • Chunfu Zheng,
  • Zhen Yang,
  • Gongguan Liu

摘要

Various high-throughput genetic functional screening and physical protein interaction screening methods have been employed to gain a global understanding of how viruses interact with host cells for replication. In this chapter, we provide an overview of the bioinformatics analysis and computational methods of virus–host interactions and highlight their advantages and disadvantages to provide a technical reference for interactive research on virus–host interactomes and the identification of antiviral factors.