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The ability to quantify binding affinity of molecular interactions is an essential component of drug development and life science research. This chapter outlines the practical use of surface plasmon resonance spectroscopy to monitor protein-protein interactions with an emphasis on basic experimental design. A short overview of common epitope binning assays is also included.

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Binding Kinetics and Epitope Binning Using Surface Plasmon Resonance

  • 实验方案

  • 发表日期：

    2025年

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  • Johan Nilvebrant

摘要

The ability to quantify binding affinity of molecular interactions is an essential component of drug development and life science research. This chapter outlines the practical use of surface plasmon resonance spectroscopy to monitor protein-protein interactions with an emphasis on basic experimental design. A short overview of common epitope binning assays is also included.