The Cancer Epitope Database and Analysis Resource (CEDAR) is a freely accessible catalog of cancer epitope and receptor data linked to the biological, immunological, and clinical contexts in which they were described. CEDAR data is populated by manual curation of the cancer literature and provides a central resource for researchers to access information about cancer antigens and their specific epitopes, which is relevant to our understanding of the role that the immune system plays in cancer progression, prevention, and treatment. In this chapter, we aim to provide a comprehensive overview of the database section of CEDAR. This includes a detailed description of all available query parameters, guidance on navigating through the query results, and a demonstration of how CEDAR can aid cancer research, featuring example research scenarios and queries.

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Using the Cancer Epitope Database and Analysis Resource (CEDAR)

  • Zeynep Koşaloğlu-Yalçın,
  • Randi Vita,
  • Nina Blazeska,
  • Bjoern Peters,
  • Alessandro Sette

摘要

The Cancer Epitope Database and Analysis Resource (CEDAR) is a freely accessible catalog of cancer epitope and receptor data linked to the biological, immunological, and clinical contexts in which they were described. CEDAR data is populated by manual curation of the cancer literature and provides a central resource for researchers to access information about cancer antigens and their specific epitopes, which is relevant to our understanding of the role that the immune system plays in cancer progression, prevention, and treatment. In this chapter, we aim to provide a comprehensive overview of the database section of CEDAR. This includes a detailed description of all available query parameters, guidance on navigating through the query results, and a demonstration of how CEDAR can aid cancer research, featuring example research scenarios and queries.