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Synthetic poly(amino acid)s are a class of promising materials for biomedical applications. Ring opening polymerization (ROP) based on N-carboxyanhydrides (NCAs) is a commonly used method for synthesizing poly(amino acid)s with controlled molecular weight distribution and tunable amino acid sequence. Herein, we introduce two representative protocols for synthesizing poly(amino acid)s with homogenous or multiblock amino acid units based on ROP.

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Synthesis of Poly(Amino Acids) Using Ring Opening Polymerization

  • 实验方案

  • 发表日期：

    2025年

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  • Pengwen Chen,
  • Guanghao Hu,
  • Horacio Cabral

摘要

Synthetic poly(amino acid)s are a class of promising materials for biomedical applications. Ring opening polymerization (ROP) based on N-carboxyanhydrides (NCAs) is a commonly used method for synthesizing poly(amino acid)s with controlled molecular weight distribution and tunable amino acid sequence. Herein, we introduce two representative protocols for synthesizing poly(amino acid)s with homogenous or multiblock amino acid units based on ROP.