Scholarlink

In conventional dendrimer synthesis, producing defective dendrimers is unavoidable. However, no synthetic method exists to prepare these defect dendrimers with a well-defined structure. A novel and efficient solid-phase method has been developed to synthesize well-defined lysine defect dendrimers using orthogonally protected lysine residues. This chapter details the synthesis of two defect lysine dendrimers. Additionally, the synthesis of a boronic acid-decorated defect lysine dendrimer is presented to demonstrate the feasibility of this method for preparing functional defect dendrimers.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Solid-Phase Synthesis of Well-Defined Defect Lysine Dendrimers

  • 实验方案

  • 发表日期：

    2025年

查看全文
  • Yong Liao,
  • Yuan-Ting Chan,
  • Yi Kai Lin,
  • Vijayasimha Molakaseema,
  • Anand Selvaraj,
  • Hui-Ting Chen,
  • Yun-Ming Wang,
  • Yeun-Mun Choo,
  • Chai-Lin Kao

摘要

In conventional dendrimer synthesis, producing defective dendrimers is unavoidable. However, no synthetic method exists to prepare these defect dendrimers with a well-defined structure. A novel and efficient solid-phase method has been developed to synthesize well-defined lysine defect dendrimers using orthogonally protected lysine residues. This chapter details the synthesis of two defect lysine dendrimers. Additionally, the synthesis of a boronic acid-decorated defect lysine dendrimer is presented to demonstrate the feasibility of this method for preparing functional defect dendrimers.