Cell therapy represents an innovative approach in regenerative medicine, utilizing living cells to treat various diseases and disorders. This therapy may involve cell replacement, as in red blood cell infusion for anemia, platelet administration, or immune system regulation through T lymphocytes. Stem cells and progenitor cells, which can create new cells, are also essential for regenerative therapies. Technologies in cell therapy, including viral vector gene modification and genome editing (such as CRISPR-Cas9), have enabled targeted treatments for blood cancers, genetic disorders, and more. Immune cell-based therapies, particularly CAR T-cell treatments, have shown promising results for cancers. Veterinary applications of cell therapy, such as ligament repair in horses, highlight the expanding potential across species. Cell therapy is still in its developmental stages, but its remarkable potential for treating cardiovascular, neurological, and immune-related disorders continues to grow. Collaboration between clinical researchers and laboratory scientists remains essential to enhance therapy efficacy and address technological challenges. This evolving field aligns with biotechnological advancements and signifies a transformative future in medicine and animal healthcare.

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Cell-Based Therapies and Drug Delivery: Advancements and Challenges

  • Pradeep Kumar Ram,
  • Amit Kumar Jha,
  • Kritika Dhial,
  • Abhishek Pathak

摘要

Cell therapy represents an innovative approach in regenerative medicine, utilizing living cells to treat various diseases and disorders. This therapy may involve cell replacement, as in red blood cell infusion for anemia, platelet administration, or immune system regulation through T lymphocytes. Stem cells and progenitor cells, which can create new cells, are also essential for regenerative therapies. Technologies in cell therapy, including viral vector gene modification and genome editing (such as CRISPR-Cas9), have enabled targeted treatments for blood cancers, genetic disorders, and more. Immune cell-based therapies, particularly CAR T-cell treatments, have shown promising results for cancers. Veterinary applications of cell therapy, such as ligament repair in horses, highlight the expanding potential across species. Cell therapy is still in its developmental stages, but its remarkable potential for treating cardiovascular, neurological, and immune-related disorders continues to grow. Collaboration between clinical researchers and laboratory scientists remains essential to enhance therapy efficacy and address technological challenges. This evolving field aligns with biotechnological advancements and signifies a transformative future in medicine and animal healthcare.