The occurrence of Listeria monocytogenes in meat-based products can result in serious health problems for consumers, making it a substantial danger to food safety. With a special focus on meat products, this review offers an overview of the techniques for recognizing and detecting L. monocytogenes in solid food. The process begins with pre-sampling preparation, including selecting sampling sites and assembling sterile equipment. Aseptic sampling from various parts of the meat product ensures representative testing. Primary enrichment in Fraser broth base encourages Listeria growth, followed by secondary enrichment and selective plating on Oxford agar and PALCAM plates. Guidelines for sample handling and transportation guarantee integrity while the sample is being transported to the lab. In summary, the significance of stringent food safety protocols in mitigating the likelihood of foodborne illnesses is highlighted by this overview. Because L. monocytogenes is persistent and adaptable to a variety of environmental situations, listeriosis poses a concern to world health. Advances in preservation technologies offer new opportunities for pathogen control, but stringent measures remain essential to mitigate contamination risks. This chapter explores evolving methodologies and challenges in isolating and detecting L. monocytogenes from solid food sources, contributing to improved food safety management.