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This chapter presents a novel approach for developing antibacterial wound dressings by electrospinning a composite of polyvinyl alcohol (PVA) and silver nitrate (AgNO₃). The three dimensional (3D) wound dressing combines the biocompatibility and favorable mechanical properties of PVA with the antibacterial properties of silver ions. The electrospinning process provides structural integrity and controlled release of silver ions to prevent bacterial infection. Mesenchymal stem cells (MSCs) are used to assess biocompatibility of electrospun 3D PVA/AgNO3 nanofiber scaffolds for tissue engineering applications.

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Electrospun Poly(vinyl alcohol)/Silver Nitrate (PVA/AgNO₃) Nanofibers Incorporated with Mesenchymal Stem Cells for Wound Dressing Applications

  • 实验方案

  • 发表日期：

    2025年

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  • Aysegul Tiryaki,
  • Ayse Ceren Calikoglu-Koyuncu

摘要

This chapter presents a novel approach for developing antibacterial wound dressings by electrospinning a composite of polyvinyl alcohol (PVA) and silver nitrate (AgNO₃). The three dimensional (3D) wound dressing combines the biocompatibility and favorable mechanical properties of PVA with the antibacterial properties of silver ions. The electrospinning process provides structural integrity and controlled release of silver ions to prevent bacterial infection. Mesenchymal stem cells (MSCs) are used to assess biocompatibility of electrospun 3D PVA/AgNO3 nanofiber scaffolds for tissue engineering applications.