Percussionists bring rhythm and intensity to music—but behind the energetic beats and dynamic movements lies a unique set of physical challenges. Unlike other instrumentalists, percussionists often engage the entire body in their performance, relying heavily on repetitive striking motions, forceful arm movements, and full-body coordination. These demands place them at risk for a range of musculoskeletal and overuse injuries, particularly in the hands, wrists, shoulders, and spine. This chapter explores the spectrum of performance-related injuries encountered by percussion musicians, from acute trauma to chronic overuse syndromes. It examines the role of technique, posture, instrument design, and practice habits in injury development, and offers evidence-based strategies for prevention, treatment, and rehabilitation. With insights drawn from clinical research and real-world musician experiences, this chapter aims to bridge the gap between rhythm and wellness—ensuring that percussionists can continue to perform without compromising their physical health.