Recent advances in computational methods and in vitro assessment have accelerated the identification and optimization of possible therapeutic agents, leading to a paradigm shift in the field of anticancer drug discovery and development. This book chapter aims to provide a thorough understanding of how pre-clinical research on anticancer therapeutics integrates computational and in vitro approaches. By highlighting the synergy between these two domains, the chapter aims to contribute to a comprehensive understanding of how these advancements are revolutionizing the landscape of anticancer drug discovery.

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Computational Advancements and In Vitro Evaluation in Pre-clinical Anticancer Drug Discovery and Development

  • Utid Suriya,
  • Boonyarut Ladda,
  • Bodee Nutho,
  • Panupong Mahalapbutr,
  • Borwornlak Toopradab,
  • Thanyada Rungrotmongkol,
  • Phitchakorn Somngam,
  • Nan Chaiyariti,
  • Tavan Janvilisri

摘要

Recent advances in computational methods and in vitro assessment have accelerated the identification and optimization of possible therapeutic agents, leading to a paradigm shift in the field of anticancer drug discovery and development. This book chapter aims to provide a thorough understanding of how pre-clinical research on anticancer therapeutics integrates computational and in vitro approaches. By highlighting the synergy between these two domains, the chapter aims to contribute to a comprehensive understanding of how these advancements are revolutionizing the landscape of anticancer drug discovery.