This chapter is devoted to the description of directions of bioimplants development in oncology, methods of their production, and materials used. The results of both own research in this field and achievements of other researchers are analyzed. Special attention is paid to the description of developments in the field of bioimplants and their scaffolds for the replacement of bone, cartilage, and trachea defects. Innovative solutions providing depot injection of bioactive components and drugs for therapy of cancer patients and preventing the development of side effects are also described. The possibilities of using extracellular matrix implants, synthetic and natural polymers, titanium alloys, and biodegradable alloys based on Fe-Mn system and magnesium for the development of scaffolds were thoroughly discussed. The properties of compact and porous scaffolds based on titanium alloys were described in detail in separate sections. Recent advances in this field have been critically analyzed, including approaches to model design, testing of the resulting developments, the possibilities of machining and 3D printing to modify the structure and properties of scaffolds, and the problems of their biocorrosion, biocompatibility, and functionality. Special attention is paid to highlighting current problems in the industry and ways to solve them.