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<p>Current treatments for rapid eye movement sleep behavior disorder are not always effective and can lead to dose-limited adverse events, and new treatments are needed for this condition. We present a case of a patient with treatment-refractory isolated rapid eye movement sleep behavior disorder who had a dramatic and sustained improvement in dream enactment behaviors using oral tinctures containing cannabidiol and tetrahydrocannabinol without adverse events over 5 years of follow-up.</p> Citation: <p>Samra S, Attarian H, Malkani R. The use of cannabinoid therapy in treatment-refractory isolated REM sleep behavior disorder: a case report. <i>J Clin Sleep Med</i>. 2025;21(7):1311–1313.</p>

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The use of cannabinoid therapy in treatment-refractory isolated REM sleep behavior disorder: a case report

  • 期刊论文

  • 发表日期：

    2025年7月1日

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  • Sahej Samra,
  • Hrayr Attarian,
  • Roneil Malkani

摘要

Current treatments for rapid eye movement sleep behavior disorder are not always effective and can lead to dose-limited adverse events, and new treatments are needed for this condition. We present a case of a patient with treatment-refractory isolated rapid eye movement sleep behavior disorder who had a dramatic and sustained improvement in dream enactment behaviors using oral tinctures containing cannabidiol and tetrahydrocannabinol without adverse events over 5 years of follow-up.

Citation:

Samra S, Attarian H, Malkani R. The use of cannabinoid therapy in treatment-refractory isolated REM sleep behavior disorder: a case report. J Clin Sleep Med. 2025;21(7):1311–1313.