Abstract <p><i>The Aim of the Review</i> is to describe the structure and peculiarities of modern primate biobanks, their role in international scientific networks, as well as specialized genomic resources for the studies on hominids and other models. The review presents modern methods for authentication and genetic passportization of biological samples, such as microsatellite and SNP analysis that provide a high accuracy of identification of individuals and quality control of materials. A special attention is paid to the importance of standardization of processes and international collaboration to improve the efficiency of studies and preserve the genetic diversity.<i>Conclusions.</i> The authors conclude that the integration of genetic information into digital ecosystems of primate biobank leads to a transition from traditional collections to intelligent platforms that use the advanced technologies of analysis and modeling, which opens up new prospects for the studies and personalized medicine.</p>

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Integration of Genetic Information into Digital Ecosystems of Modern Primate Biobanks: Problems and Prospects

  • M. V. Patrushev,
  • A. V. Prokopenko,
  • A. O. Izotova,
  • A. A. Agumava,
  • D. S. Petrova,
  • I. V. Matyushkin,
  • O. P. Chzhu,
  • F. S. Sharko,
  • S. V. Toshchakov

摘要

Abstract

The Aim of the Review is to describe the structure and peculiarities of modern primate biobanks, their role in international scientific networks, as well as specialized genomic resources for the studies on hominids and other models. The review presents modern methods for authentication and genetic passportization of biological samples, such as microsatellite and SNP analysis that provide a high accuracy of identification of individuals and quality control of materials. A special attention is paid to the importance of standardization of processes and international collaboration to improve the efficiency of studies and preserve the genetic diversity.Conclusions. The authors conclude that the integration of genetic information into digital ecosystems of primate biobank leads to a transition from traditional collections to intelligent platforms that use the advanced technologies of analysis and modeling, which opens up new prospects for the studies and personalized medicine.