Scholarlink

<p>Tomographic volumetric bioprinting (TVBP) is an emerging transformative technology in bio-manufacturing, distinguished by two exceptional capabilities: ultrafast fabrication (centimeter-scale constructs within tens of seconds) and unique compatibility with ultra-soft bioinks (&lt;10<sup>2</sup> Pa). Despite its potential, TVBP remains in its infancy because of significant hurdles. These include the need to adapt conventional photocurable bioinks to TVBP’s unique photopolymerization requirements and achieve sufficient resolution to replicate intricate multicellular structures. Therefore, this review outlines strategies to address these challenges, delving into (1) the development of suitable bioinks, (2) printing resolution optimization, and (3) rapid construction of complex biological structures and functions. Furthermore, the fundamental principles and evolution of projection slicing algorithms are explored, and the latest advancements in TVBP applications are summarized. Finally, we explore the future trajectory of this promising bio-manufacturing technology.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Tomographic volumetric bioprinting: from bioink design to resolution enhancement

  • 期刊论文

  • 发表日期：

    2026年5月25日

查看全文
  • Qilin Wu,
  • Chaofan He,
  • Tianhong Qiao,
  • Yuewei Chen,
  • Hongyao Shen,
  • Yong He

摘要

Tomographic volumetric bioprinting (TVBP) is an emerging transformative technology in bio-manufacturing, distinguished by two exceptional capabilities: ultrafast fabrication (centimeter-scale constructs within tens of seconds) and unique compatibility with ultra-soft bioinks (<102 Pa). Despite its potential, TVBP remains in its infancy because of significant hurdles. These include the need to adapt conventional photocurable bioinks to TVBP’s unique photopolymerization requirements and achieve sufficient resolution to replicate intricate multicellular structures. Therefore, this review outlines strategies to address these challenges, delving into (1) the development of suitable bioinks, (2) printing resolution optimization, and (3) rapid construction of complex biological structures and functions. Furthermore, the fundamental principles and evolution of projection slicing algorithms are explored, and the latest advancements in TVBP applications are summarized. Finally, we explore the future trajectory of this promising bio-manufacturing technology.