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<p>Hypersensitivity to an implanted cardiac pacemaker is an uncommon condition that may clinically resemble acute coronary syndrome or device-related infection. This complication requires complete system removal generating substantial healthcare costs and multiple procedure-related actions. Polymethylmethacrylate (PMMA) is a synthetic polymer widely used in biomedical applications while copper oxide nanoparticles (CuO-NPs), have shown efficacy in reducing microbial adhesion, providing abrasion resistance, and improving coating adhesion to different surfaces. In this study, the effect of a PMMA/CuO-NPs coating on titanium sheets was evaluated to assess anticorrosive performance in simulated biological environments. The CuO-NPs were synthesized using an aqueous extract of purple basil (<i>Ocimum basilicum</i>) and characterized by UV–vis spectroscopy, SEM, and FTIR. Assessment by electrochemical techniques in simulated body fluid (SBF) at 36 ± 0.5&#xa0;°C in a three-electrode cell was performed to evaluate their corrosion resistance. The composite coating demonstrated promising potential for its use in tissue engineering applications.</p> Graphical abstract <p></p>

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Synthesis and electrochemical assessment of a PMMA/CuO-NPs composite coating

  • 期刊论文

  • 发表日期：

    2026年2月9日

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  • P. G. Cuevas-Martínez,
  • G. Carbajal de la Torre,
  • M. L. Ballesteros-Almanza,
  • I. Maldonado-Garcia,
  • M. A. Espinosa-Medina,
  • N. N. Zurita-Méndez

摘要

Hypersensitivity to an implanted cardiac pacemaker is an uncommon condition that may clinically resemble acute coronary syndrome or device-related infection. This complication requires complete system removal generating substantial healthcare costs and multiple procedure-related actions. Polymethylmethacrylate (PMMA) is a synthetic polymer widely used in biomedical applications while copper oxide nanoparticles (CuO-NPs), have shown efficacy in reducing microbial adhesion, providing abrasion resistance, and improving coating adhesion to different surfaces. In this study, the effect of a PMMA/CuO-NPs coating on titanium sheets was evaluated to assess anticorrosive performance in simulated biological environments. The CuO-NPs were synthesized using an aqueous extract of purple basil (Ocimum basilicum) and characterized by UV–vis spectroscopy, SEM, and FTIR. Assessment by electrochemical techniques in simulated body fluid (SBF) at 36 ± 0.5 °C in a three-electrode cell was performed to evaluate their corrosion resistance. The composite coating demonstrated promising potential for its use in tissue engineering applications.

Graphical abstract