Scholarlink

<p>Biofilms cause life-threatening infections and contaminations, and traditional antimicrobial coatings suffer from biofouling as the formation of conditioning layer by cell debris. We developed a metal-coordinating polymer of poly(methacrylic acid) with Ag<sup>+</sup>, achieving both antimicrobial and antifouling properties. It reduced the viability of <i>Pseudomonas aeruginosa</i>, 70% of biofilm formation, and apparent toxicity that is demonstrated by 97% viability of human dermal fibroblasts (HDFa) treated by the supernatants from bacteria grown on the coating, compared to 8% on uncoated surfaces. Synthesized <i>via</i> initiated chemical vapor deposition (iCVD), this coating offers a scalable, substrate-independent solution for applications in healthcare and food manufacturing.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A dual-functional antimicrobial and antifouling coating enabled by metal-coordinating polymer thin films

  • 期刊论文

  • 发表日期：

    2025年3月20日

查看全文
  • Pengyu Chen,
  • Haonian Shu,
  • Yifan Cheng,
  • Katie Munechika,
  • Rong Yang

摘要

Biofilms cause life-threatening infections and contaminations, and traditional antimicrobial coatings suffer from biofouling as the formation of conditioning layer by cell debris. We developed a metal-coordinating polymer of poly(methacrylic acid) with Ag+, achieving both antimicrobial and antifouling properties. It reduced the viability of Pseudomonas aeruginosa, 70% of biofilm formation, and apparent toxicity that is demonstrated by 97% viability of human dermal fibroblasts (HDFa) treated by the supernatants from bacteria grown on the coating, compared to 8% on uncoated surfaces. Synthesized via initiated chemical vapor deposition (iCVD), this coating offers a scalable, substrate-independent solution for applications in healthcare and food manufacturing.

Graphical abstract