<p>Iron (Fe) solubilization and reduction are essential for bacterial survival, growth, and virulence. Additionally, these two processes significantly impact bacterial community dynamics and the bioreduction of toxic metals (TMs). To ensure a comprehensive and balanced overview of iron solubilization and bacterial bioremediation of TMs, we self-assessed our literature search according to the criteria outlined in Item 3 (Description of the Literature Search) of the Scale for the Assessment of Narrative Review Articles (SANRA) checklist. From data synthesis, we describe iron solubilization and the active transport mechanisms used by bacteria to scavenge ferric iron (Fe³⁺), as well as the internalization of ferric iron through specialized receptors. Our findings highlight that the internalization and reduction of ferric iron to ferrous iron (Fe²⁺) are pivotal for the biosynthesis of cofactors required for metabolic and enzymatic activities in bacteria. In soil environments, iron species influence iron solubilization and thus act as major drivers of microbial abundance, interspecies interactions, and community structure. However, contamination by TMs further disrupts these homeostatic processes, triggering metabolic stress and iron starvation responses. This review evaluates how iron solubilization and reduction, coupled with innate bacterial resistance, facilitate the remediation of TMs. Also, we report that iron plaque, organic amendments, manganese oxides, and nano-zerovalent iron (nZVI or Fe⁰) are important strategies that enhance bacterial-mediated reduction of TMs. In summary, bacterial iron solubilization and reduction are not only central and critical mechanisms in microbial ecology but also promising when incorporated into advanced strategies for the sustainable remediation of TM-contaminated soils.</p>