<p>Sustainable cellular manufacturing (SCM) is the combination of sustainability and cellular manufacturing (CM) which helps to achieve the numerous benefits of CM as well as remains concern about environmental, technological and social issues. Bangladesh is an emerging economy and the readymade garments (RMG) industries of Bangladesh growing very rapidly. In this emerging economy and competitive market of RMG industries, implementation of SCM is very important but conversion of traditional processes to excellent processes like CM is a challenging task. Identifying the barriers for implementing SCM will help manufacturers, engineers and managers to successfully overcome the challenges. In this research, barriers for implementing SCM in Bangladeshi RMG industries have been analyzed. 11 most significant barriers have been extracted using principal component analysis (PCA) from 28 barriers which have been gathered from research papers, expert advice and brainstorming. PCA has been used to identify and rank the barriers using XLSTAT software. Interpretive structural modelling (ISM) and Matrice d'Impacts Croises Multiplication Appliques a un Classement (MICMAC) approach have been applied to uncover the interdependencies and determine the driving power of the barriers. To the best of our knowledge, this type of study is totally new of its kind that analyzed the barriers for implementing SCM in Bangladeshi RMG industries. This research may help industrial managers, decision makers and practitioners in the Bangladeshi RMG industries to realize the challenges confronting them when trying to implement SCM and enable them to address these challenges to prevent for a successful implementation of SCM.</p>