<p>Lensless imaging offers a scalable, hardware-light route to optical microscopy but has largely remained structural. In a recent study, Wang et al<i>.</i> demonstrate that molecular specificity can be intrinsically encoded and computationally recovered within a fully lensless framework. This work reframes lensless imaging from scaling structure to encoding function, highlighting an emerging paradigm in which optical simplicity and information completeness are co-designed through optics and computation.</p>

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From high-throughput imaging to functional insight: lensless imaging moves beyond structure

  • Jiaming Qian,
  • Jiasong Sun,
  • Qian Chen,
  • Chao Zuo

摘要

Lensless imaging offers a scalable, hardware-light route to optical microscopy but has largely remained structural. In a recent study, Wang et al. demonstrate that molecular specificity can be intrinsically encoded and computationally recovered within a fully lensless framework. This work reframes lensless imaging from scaling structure to encoding function, highlighting an emerging paradigm in which optical simplicity and information completeness are co-designed through optics and computation.