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<p>This study established a method to analyze microplastics (MPs) in rat feces to evaluate the effects of MP size on their excretion after oral ingestion. Using this method, a high recovery rate (&gt; 80%) was achieved via the addition of an enzymatic digestion step after treatment with potassium hydroxide. With particle sizes ranging from 30 to 200&#xa0;μm, the fecal excretion rate of MPs was analyzed. Smaller MPs (30 and 50&#xa0;μm) had a significantly lower excretion rate compared with that of larger MPs (200&#xa0;μm).</p>

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Effects of excretion of different sizes of orally ingested microplastics in rats

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月16日

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  • Di Liu,
  • Shinya Kitamura,
  • Atsushi Yasuda,
  • Hongye Zhang,
  • Emiko Fujita,
  • Yutaka Kameda,
  • Muneshige Shimizu

摘要

This study established a method to analyze microplastics (MPs) in rat feces to evaluate the effects of MP size on their excretion after oral ingestion. Using this method, a high recovery rate (> 80%) was achieved via the addition of an enzymatic digestion step after treatment with potassium hydroxide. With particle sizes ranging from 30 to 200 μm, the fecal excretion rate of MPs was analyzed. Smaller MPs (30 and 50 μm) had a significantly lower excretion rate compared with that of larger MPs (200 μm).