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Background <p>Non-Hodgkin lymphomas are a group of hematological malignancies that result from the uncontrolled proliferation of lymphoid cells. These malignancies are classified into different types based on histological structure and tumor cell type. This work describes a rare case of anaplastic large T cell lymphoma in an unusual anatomic location, the parotid gland. We have reported this case not through the classical presentation of patient information. Instead, we used the immunohistochemical description of the biopsy.</p> Results <p>The immunohistochemical study of parotid gland biopsy revealed an anaplastic large cell T-lymphoma with a CD3+, CD30+, and ALK− phenotype.</p> Conclusion <p>Anaplastic large cell lymphoma is a rare type of lymphoma. Its localization in the parotid gland is even rarer.</p>

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Anaplastic large T cell lymphoma presenting in the parotid gland: a diagnostic challenge

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年1月27日

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  • Karima Bouali,
  • Sebti Boulekzaz,
  • Donia Lina Chenafi,
  • Meriem Boulechfar,
  • Leila Beddar,
  • Ibtissem El Ouar

摘要

Background

Non-Hodgkin lymphomas are a group of hematological malignancies that result from the uncontrolled proliferation of lymphoid cells. These malignancies are classified into different types based on histological structure and tumor cell type. This work describes a rare case of anaplastic large T cell lymphoma in an unusual anatomic location, the parotid gland. We have reported this case not through the classical presentation of patient information. Instead, we used the immunohistochemical description of the biopsy.

Results

The immunohistochemical study of parotid gland biopsy revealed an anaplastic large cell T-lymphoma with a CD3+, CD30+, and ALK− phenotype.

Conclusion

Anaplastic large cell lymphoma is a rare type of lymphoma. Its localization in the parotid gland is even rarer.