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Background <p>The albumin-bilirubin (ALBI) grade was initially developed as a prognostic tool for hepatocellular carcinoma and is increasingly recognized for assessing liver function and surgical risk.</p> Objective <p>To evaluate the relationship between preoperative ALBI grade and length of hospital and intensive care unit stay after deceased-donor liver transplantation (LT).</p> Methods <p>This retrospective study included 162 adult patients who underwent LT from brain-dead donors at our center between 2018 and 2023. Exclusion criteria were LT due to acute liver failure, re-transplantation, and simultaneous liver–kidney transplantation. ALBI grades (1, 2, 3) were calculated from pre-LT serum albumin and bilirubin levels. Demographic, intraoperative, and postoperative data—including hospital and intensive care unit lengths of stay and inhospital mortality—were analyzed.</p> Results <p>Among patients, 4 (2.5%) were ALBI-1, 70 (43.2%) ALBI-2, and 88 (54.3%) ALBI-3. ALBI grade 3 was significantly associated with longer hospital stay post-LT (<i>β</i> = 7.420, 95% <i>CI</i> 2.407–12.434, <i>p</i> = 0.004) compared with lower grades. No significant association was found between ALBI grade and intensive care unit stay (grade 3: <i>β</i> = 0.432, <i>p</i> = 0.535; grade 2: <i>β</i> = −0.221, <i>p</i> = 0.723) compared with grade 1.</p> Conclusion <p>ALBI grade 3 predicts longer hospital stay but not ICU stay after LT, suggesting that the ALBI grade may serve as a useful predictor for posttransplant hospitalization duration.</p>

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Impact of preoperative albumin-bilirubin grade on posttransplant hospitalization in adult liver transplant recipients

  • 期刊论文

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  • 发表日期：

    2026年1月29日

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  • Sepideh Yazdanfar,
  • Soheila Milani,
  • Malihe Aghasizadeh

摘要

Background

The albumin-bilirubin (ALBI) grade was initially developed as a prognostic tool for hepatocellular carcinoma and is increasingly recognized for assessing liver function and surgical risk.

Objective

To evaluate the relationship between preoperative ALBI grade and length of hospital and intensive care unit stay after deceased-donor liver transplantation (LT).

Methods

This retrospective study included 162 adult patients who underwent LT from brain-dead donors at our center between 2018 and 2023. Exclusion criteria were LT due to acute liver failure, re-transplantation, and simultaneous liver–kidney transplantation. ALBI grades (1, 2, 3) were calculated from pre-LT serum albumin and bilirubin levels. Demographic, intraoperative, and postoperative data—including hospital and intensive care unit lengths of stay and inhospital mortality—were analyzed.

Results

Among patients, 4 (2.5%) were ALBI-1, 70 (43.2%) ALBI-2, and 88 (54.3%) ALBI-3. ALBI grade 3 was significantly associated with longer hospital stay post-LT (β = 7.420, 95% CI 2.407–12.434, p = 0.004) compared with lower grades. No significant association was found between ALBI grade and intensive care unit stay (grade 3: β = 0.432, p = 0.535; grade 2: β = −0.221, p = 0.723) compared with grade 1.

Conclusion

ALBI grade 3 predicts longer hospital stay but not ICU stay after LT, suggesting that the ALBI grade may serve as a useful predictor for posttransplant hospitalization duration.