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Background <p>Infective endocarditis (IE) remains a serious and potentially life-threatening condition. Fungal infective endocarditis is a rare form of endocarditis that occur in immunodeficient patients. Atrial myxoma are a common cause of cardiac tumors in the left atrium. However, infective endocarditis is a differential diagnosis of cardiac masses in general and atrial myxoma particularly.</p> Case summary <p>A 49-year-old male with subacute infective endocarditis presentation underwent an echocardiogram examination that showed a left atrial mass with features of atrial myxoma. However, the histological examination after surgical removal of the mass showed a fungal mass.</p> Conclusion <p>This case shows that a fungal infective endocarditis may present with a cardiac mass sharing typical features with left atrial myxoma. It also shows the importance of histological examination for the final diagnosis and a prompt treatment.</p>

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Left atrial fungal mass masquerading as myxoma: the importance of histopathological confirmation: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月18日

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  • MOHAMED MOUNIR NESNASSI,
  • Asmae Benssied,
  • Inasse Bargach,
  • Siham Hallab,
  • Safae Hilal,
  • Ibtissam Fellat,
  • Mohamed Cherti

摘要

Background

Infective endocarditis (IE) remains a serious and potentially life-threatening condition. Fungal infective endocarditis is a rare form of endocarditis that occur in immunodeficient patients. Atrial myxoma are a common cause of cardiac tumors in the left atrium. However, infective endocarditis is a differential diagnosis of cardiac masses in general and atrial myxoma particularly.

Case summary

A 49-year-old male with subacute infective endocarditis presentation underwent an echocardiogram examination that showed a left atrial mass with features of atrial myxoma. However, the histological examination after surgical removal of the mass showed a fungal mass.

Conclusion

This case shows that a fungal infective endocarditis may present with a cardiac mass sharing typical features with left atrial myxoma. It also shows the importance of histological examination for the final diagnosis and a prompt treatment.