Scholarlink

Objectives <p>Bariatric surgery is a long-term treatment for obesity that leads to significant weight loss that impacts reproductive health. This study explored how bariatric surgery affects pregnancy rates post-surgery.</p> Methods <p>This retrospective study was conducted at Bahrain Defense Force Hospital in 2009–2022 and included 310 women of reproductive age who had bariatric surgery (including sleeve gastrectomy, gastric banding, and gastric bypass) before planning pregnancy. Data were analyzed using Statdirect software (version 3.3.5 22/03/2021), with <i>p</i> &lt; 0.05 considered significant.</p> Results <p>Of 310 patients who underwent bariatric surgery, 35.8% (111 patients) achieved pregnancy. Those with successful pregnancies had higher pre-surgery weight and body mass index (BMI) and a greater BMI drop (35.3%) compared to 29.4% (199) of non-pregnant patients (<i>P</i> &lt; 0.0001). Receiver operating characteristic (ROC) curve analysis indicated that a BMI-loss cutoff of 34.6% was associated with pregnancy (sensitivity 61%, specificity 64%). Logistic regression was performed according to this cutoff value to exclude any other contributing factors, including age ≤ 35 years, BMI ≤ 30, and use of artificial reproductive therapy (ART) to achieve pregnancy; the analysis results were not statistically significant for all of the factors (age ≤ 35 years, BMI ≤ 30, and use of ART). Simple linear regression showed no correlation between pre-surgery weight, total weight loss, percentage of BMI loss, and the time required to achieve pregnancy after bariatric surgery (<i>P</i> = 0.95, <i>P</i> = 0.25, and <i>P</i> = 0.72).</p> Conclusion <p>Higher pre-surgery BMI and greater BMI loss may be associated with higher pregnancy success after bariatric surgery.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

For women with significant obesity, does bariatric surgery enhance fertility, a retrospective cohort study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年11月18日

查看全文
  • Eman Bahaa Elgendy,
  • Reem Abdulla Abduljalil,
  • Sharefa Adel Alansari,
  • Bayan Ali Abdulla Alsharqi,
  • Fatema Abdulaziz Sharif,
  • Nawal Dayoub

摘要

Objectives

Bariatric surgery is a long-term treatment for obesity that leads to significant weight loss that impacts reproductive health. This study explored how bariatric surgery affects pregnancy rates post-surgery.

Methods

This retrospective study was conducted at Bahrain Defense Force Hospital in 2009–2022 and included 310 women of reproductive age who had bariatric surgery (including sleeve gastrectomy, gastric banding, and gastric bypass) before planning pregnancy. Data were analyzed using Statdirect software (version 3.3.5 22/03/2021), with p < 0.05 considered significant.

Results

Of 310 patients who underwent bariatric surgery, 35.8% (111 patients) achieved pregnancy. Those with successful pregnancies had higher pre-surgery weight and body mass index (BMI) and a greater BMI drop (35.3%) compared to 29.4% (199) of non-pregnant patients (P < 0.0001). Receiver operating characteristic (ROC) curve analysis indicated that a BMI-loss cutoff of 34.6% was associated with pregnancy (sensitivity 61%, specificity 64%). Logistic regression was performed according to this cutoff value to exclude any other contributing factors, including age ≤ 35 years, BMI ≤ 30, and use of artificial reproductive therapy (ART) to achieve pregnancy; the analysis results were not statistically significant for all of the factors (age ≤ 35 years, BMI ≤ 30, and use of ART). Simple linear regression showed no correlation between pre-surgery weight, total weight loss, percentage of BMI loss, and the time required to achieve pregnancy after bariatric surgery (P = 0.95, P = 0.25, and P = 0.72).

Conclusion

Higher pre-surgery BMI and greater BMI loss may be associated with higher pregnancy success after bariatric surgery.