Background <p>The foramen rotundum lies inferior and posterior to the medial end of the superior orbital fissure and extends forward into the pterygopalatine fossa, through which the maxillary nerve passes. It represents the edge between the endocranial and exocranial spaces and is related to pathologies of tumours. When one considers the delicate neurovascular structures that traverse their narrow confines, knowledge of the variations of these foramina becomes an important part of diagnostic medicine and an aid to the evaluation of radiologic films. This study endeavoured to investigate the morphometry and morphological variations of the foramen rotundum using defined measurement parameters.</p> Methods <p>This was a cross-sectional, observational study conducted on a total of 200 axial section head CT scans retrieved from the Picture Archiving and Communication System (PACS). Computer-assisted measurements of foraminal parameters were obtained bilaterally. Data was statistically analysed using the unpaired <i>t</i>-test, paired <i>t</i>‐test, and analysis of variance (ANOVA).</p> Result <p>The foramen ovale was examined in 110 male and 90 female CT scans. In 95% of CT scans, foramen rotundum was found as a canal, and in only 5% of cases, it was seen as a rounded foramen. The mean length, diameter at the cranial side, and distance from the mid-sagittal plane in males were 5.67 ± 1.43, 2.65 ± 0.57 (<i>p</i> = 0.031), and 17.03 ± 2.09, and in females were 5.82 ± 1.69 (<i>p</i> = 0.001), 2.63 ± 0.48, and 16.27 ± 2.09 (<i>p</i> = 0.011), respectively.</p> Conclusion <p>Among males, the length of the foramen rotundum was more on the left side, and in females, the length and width of the intracranial opening were more on left side; both were statistically significant. Understanding the normal morphometry of the foramen rotundum is fundamental for accurate assessment and safe management of related cranial pathologies.</p>