Background <p>3D printing is increasingly utilized in medical education, providing a hands-on approach to anatomical learning, surgical planning, and interdisciplinary collaboration. Despite growing interest, standardized curricula incorporating 3D printing into medical education are lacking.</p> Methods <p>A multidisciplinary team of medical educators, engineers, and students developed three distinct curricular models to integrate 3D printing into undergraduate medical education. These models include (1) integration into anatomy coursework, (2) a fourth-year clerkship elective, and (3) a pre-clerkship elective. The outline for each curriculum was designed to be adaptable across institutions, emphasizing hands-on learning, imaging segmentation, basic elements of computer-aided design (CAD), and 3D printing applications in clinical care.</p> Results <p>The proposed curricula outlined provide structured pathways for incorporating 3D printing into medical education, enhancing student engagement and comprehension of complex anatomical structures. By integrating 3D printing into anatomy courses, clerkships, and elective rotations, students gain critical skills applicable to future clinical practice. The curricular models vary in scope and resource requirements, offering flexibility for adoption across medical schools.</p> Conclusions <p>Standardizing 3D printing curricula in medical education enhances anatomical understanding, promote interdisciplinary collaboration, and prepare students for future applications of this technology in clinical practice. Our framework serves as a guide for institutions seeking to implement 3D printing curricula, fostering innovation and hands-on learning opportunities for medical trainees.</p> Trial registration <p>Not applicable.</p> Clinical trial number <p>Not applicable.</p>