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Introduction <p>The COVID-19 pandemic has significantly impacted disease burdens, yet updated nocturia epidemiological data remain limited. This study characterized age-sex-race disparities in nocturia prevalence and evaluated pandemic-related temporal changes.</p> Methods <p>Using NHANES data (2017–2023), this cross-sectional study included 10,946 adults (≥ 20&#xa0;years). Primary outcomes were nocturia prevalence (≥ 1 and ≥ 2 nightly episodes). Analyses incorporated sampling weights and multivariable logistic regression.</p> Results <p>Overall weighted prevalence reached 71.9% for nocturia (≥ 1 time/night) and 31.2% for clinical nocturia (≥ 2 times/night). Post-pandemic surge was significant: nocturia increased from 70.0% to 75.3% (<i>P</i> = 0.002) and clinical nocturia from 28.5 to 36.0% (<i>P</i> &lt; 0.001) (2017–2020 vs. 2021–2023). Young males showed the steepest clinical nocturia escalation (11.6–24.1%, <i>P</i> = 0.001), while middle-aged females experienced significant increases in overall nocturia (70.2–77.1%, <i>P</i> = 0.054). Racial disparities widened post-pandemic, with Hispanic populations demonstrating a 43.5% increase in clinical nocturia (26.9–38.6%, <i>P</i> &lt; 0.001). Multivariable regression confirmed obesity as an independent risk factor (OR = 1.312, 95% CI 1.119–1.539, <i>P</i> = 0.002). Obesity-related exacerbation intensified during the pandemic: obese males experienced a 38.9% surge in nocturia (54.5–75.7%, <i>P</i> = 0.005) and 201% increase in clinical nocturia (10.4–31.3%, <i>P</i> = 0.007).</p> Conclusions <p>Nocturia prevalence escalated markedly post-pandemic, disproportionately affecting young and obese males. Targeted interventions addressing metabolic health and socioeconomic disparities are urgently needed.</p>

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The COVID-19 impact on nocturia epidemiology: a national health survey analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月15日

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  • Junzhe Ke,
  • Junlong Huang,
  • Juncong Xie,
  • Zheng Liu,
  • Chi Zhang,
  • Xiangfu Zhou,
  • Wenshuang Li,
  • Bolong Liu

摘要

Introduction

The COVID-19 pandemic has significantly impacted disease burdens, yet updated nocturia epidemiological data remain limited. This study characterized age-sex-race disparities in nocturia prevalence and evaluated pandemic-related temporal changes.

Methods

Using NHANES data (2017–2023), this cross-sectional study included 10,946 adults (≥ 20 years). Primary outcomes were nocturia prevalence (≥ 1 and ≥ 2 nightly episodes). Analyses incorporated sampling weights and multivariable logistic regression.

Results

Overall weighted prevalence reached 71.9% for nocturia (≥ 1 time/night) and 31.2% for clinical nocturia (≥ 2 times/night). Post-pandemic surge was significant: nocturia increased from 70.0% to 75.3% (P = 0.002) and clinical nocturia from 28.5 to 36.0% (P < 0.001) (2017–2020 vs. 2021–2023). Young males showed the steepest clinical nocturia escalation (11.6–24.1%, P = 0.001), while middle-aged females experienced significant increases in overall nocturia (70.2–77.1%, P = 0.054). Racial disparities widened post-pandemic, with Hispanic populations demonstrating a 43.5% increase in clinical nocturia (26.9–38.6%, P < 0.001). Multivariable regression confirmed obesity as an independent risk factor (OR = 1.312, 95% CI 1.119–1.539, P = 0.002). Obesity-related exacerbation intensified during the pandemic: obese males experienced a 38.9% surge in nocturia (54.5–75.7%, P = 0.005) and 201% increase in clinical nocturia (10.4–31.3%, P = 0.007).

Conclusions

Nocturia prevalence escalated markedly post-pandemic, disproportionately affecting young and obese males. Targeted interventions addressing metabolic health and socioeconomic disparities are urgently needed.