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Background <p><i>Gordonia</i> spp. is a rare infectious disease that has been reported in only 18 cases to date as a cause of peritoneal dialysis-related peritonitis. This is the first report of peritonitis associated with peritoneal dialysis caused by <i>Gordonia otitidis</i> and is a valuable case in which long-term intravenous vancomycin administration was successful.</p> Case presentation <p>A 48-year-old female started peritoneal dialysis at the age of 47&#xa0;years owing to end-stage renal failure caused by chronic glomerulonephritis. She was hospitalized for peritonitis 3&#xa0;months after the start of dialysis. We administered cefazolin and ceftazidime intravenously and detected <i>Gordonia otitidis</i> in the drainage fluid after long-term culture for approximately 6&#xa0;days. Therefore, we switched to vancomycin and treated the patient intravenously for a total of 6&#xa0;weeks while checking blood levels and trough values in the drainage fluid. The patient had an increase in the number of draining cells for 3&#xa0;weeks after the start of treatment, but the number of draining cells improved after that, and no relapse was observed 6&#xa0;months after the end of treatment, suggesting that the treatment was successful.</p> Conclusions <p>When encountering peritoneal dialysis-associated peritonitis for the <i>Gordonia</i> genus, long-term intravenous administration of vancomycin should be considered as one of the treatments.</p>

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The first case of peritoneal dialysis-associated peritonitis caused by Gordonia otitidis

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  • 发表日期：

    2025年9月4日

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  • Tomoaki Miyazaki,
  • Kei Matsumoto,
  • Shugo Aoki,
  • Akiko Takeshima

摘要

Background

Gordonia spp. is a rare infectious disease that has been reported in only 18 cases to date as a cause of peritoneal dialysis-related peritonitis. This is the first report of peritonitis associated with peritoneal dialysis caused by Gordonia otitidis and is a valuable case in which long-term intravenous vancomycin administration was successful.

Case presentation

A 48-year-old female started peritoneal dialysis at the age of 47 years owing to end-stage renal failure caused by chronic glomerulonephritis. She was hospitalized for peritonitis 3 months after the start of dialysis. We administered cefazolin and ceftazidime intravenously and detected Gordonia otitidis in the drainage fluid after long-term culture for approximately 6 days. Therefore, we switched to vancomycin and treated the patient intravenously for a total of 6 weeks while checking blood levels and trough values in the drainage fluid. The patient had an increase in the number of draining cells for 3 weeks after the start of treatment, but the number of draining cells improved after that, and no relapse was observed 6 months after the end of treatment, suggesting that the treatment was successful.

Conclusions

When encountering peritoneal dialysis-associated peritonitis for the Gordonia genus, long-term intravenous administration of vancomycin should be considered as one of the treatments.